Identifier: diseasesofinfa00kopl (find matches)
Title: The diseases of infancy and childhood
Year: 1910 (1910s)
Authors: Koplik, Henry, 1858- (from old catalog)
Subjects: Children
Publisher: New York and Philadelphia, Lea & Febiger
Contributing Library: The Library of Congress
Digitizing Sponsor: The Library of Congress

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. According to the recent studies of Dolega, His, andBernard, their pathologic anatomy is also similar. Endemic cre-tinism is an advanced stage of a degeneration beginning with goitremanifestations. The resulting changes are due to athyreosis, asuspension or disturbance of the functions of the thyroid gland.Sporadic cretinism, although also due to athyreosis, occurs withoutgoitre. The peculiar formation of the skull in cretinism, endemic orsporadic, is now known not to be due to a premature synostosis of theos basilare and the sphenoid, as was at first thought by Virchow. The DISEASES OF THE THYROID GLAND. 719 brachycephalic skull as manifested in a broadening of the bridge ofthe nose, and the prognathous expression are due to a deficient growthof the bones at the base of the skull, in their long axes. The suturesand fontanelles remain open for a long time. Dentition is delayed,The skin is myxedematous in sporadic cretinism only. Dwarfismand anamria are common to both forms. Fig. 163.
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Enlarged thyroid in a child. Sporadic Cretinism.—Occurrence.—The disease may appear inutero or at any time after birth. Fully one-half of the cases developbefore the eighteenth month (Fletcher BeachV Symptoms.—I have published cases in which the symptoms wereevident within a month or five weeks after birth. The history wasas follows: In one case there was another cretin in the family; inthe others there was no such history. The birth as a rule was nor-mal (Fig. 149). The infant was jaundiced, but fairly well nour-ished. It lay in a torpid state and was only roused when severelyteased. The infant was easily chilled. The cry was deep ami coarse. 720 LYMPH-NODES, DUCTLESS GLANDS AND BLOOD. The forehead was low and narrow. The eyelids were puffy. Thetongue was large, broad, and thick, at times protruding from themouth. The abdomen was large, and the thighs and legs were outof proportion to the length of the trunk. The skin had a greenishhue. The thyroid gland could not be found. The

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